Keratinocyte Apoptosis is Decreased in Psoriatic Epidermis

Tatlican S., Arikok A. T., Gulbahar Ö., Eren C., Ulukaradag Z., Eskioglu F.

TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, cilt.43, sa.4, ss.167-170, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 4
  • Basım Tarihi: 2009
  • Dergi Adı: TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.167-170
  • Anahtar Kelimeler: Apoptosis, cell proliferation, psoriasis, CELL-DEATH, PROLIFERATION, SURVIVIN, PLAQUES, PROTEIN
  • Gazi Üniversitesi Adresli: Evet

Özet

Background and Design: Abnormal differentiation and hyperproliferation of keratinocytes are the hallmarks of psoriasis vulgaris. Although psoriasis vulgaris is generally accepted as a disease of decreased keratinocyte apoptosis, the results are contradictory. The aim of the current study is to investigate whether decreased keratinocyte apoptosis contributes to the formation of a thickened epidermis as increased keratinocyte proliferation