Keratinocyte Apoptosis is Decreased in Psoriatic Epidermis


Tatlican S., Arikok A. T. , Gulbahar Ö. , Eren C., Ulukaradag Z., Eskioglu F.

TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, vol.43, no.4, pp.167-170, 2009 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 4
  • Publication Date: 2009
  • Title of Journal : TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY
  • Page Numbers: pp.167-170
  • Keywords: Apoptosis, cell proliferation, psoriasis, CELL-DEATH, PROLIFERATION, SURVIVIN, PLAQUES, PROTEIN

Abstract

Background and Design: Abnormal differentiation and hyperproliferation of keratinocytes are the hallmarks of psoriasis vulgaris. Although psoriasis vulgaris is generally accepted as a disease of decreased keratinocyte apoptosis, the results are contradictory. The aim of the current study is to investigate whether decreased keratinocyte apoptosis contributes to the formation of a thickened epidermis as increased keratinocyte proliferation