Heparin-induced thrombocytopenia leading to stroke, lower extremity arterial occlusive disease, and skin necrosis: A case report

NAZLIEL B. , Caglayan H. Z. , Capraz I. Y. , Irkec C., Yagci M., Gesoglu T.

PLATELETS, cilt.25, sa.2, ss.129-131, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3109/09537104.2013.779655
  • Dergi Adı: PLATELETS
  • Sayfa Sayıları: ss.129-131


Enoxaparin sodium is a low molecular weight heparin (LMWH) used to treat and prevent deep venous thrombosis (DVT). The common complications related to the use of heparin are bleeding, allergic reaction, and osteoporosis. A less common complications are thrombocytopenia and thromboembolism that may not be generally recognized. We present a case of low molecular weight (LMW) heparin-induced thrombocytopenia (HIT) causing stroke, lower extremity arterial occlusion, and skin necrosis. Monitoring the platelet count is essential for early diagnosis of HIT. All patients who undergo heparinization should have a baseline platelet count done before the regimen is started and should be monitored closely especially during the first weeks of treatment.