Temporal variation of oxidant stress in critically ill patients

Gunaydin B., Sancak B., Candan S., Sariahmetoglu M., Ozcagli G., Tunctan B., ...More

MINERVA ANESTESIOLOGICA, vol.73, no.5, pp.261-266, 2007 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 5
  • Publication Date: 2007
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.261-266


Aim. Our aim was to investigate indicators of lipid peroxidation via observing temporal changes or daily fluctuations in cytoprotective enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX), and serum components possessing antioxidant activity against free radicals and malondialdehyde (MDA) such as uric acid. This study was conducted in a small number of critically ill patients versus healthy volunteers in order to design an effective antioxidant therapy regimen under oxidative stress.