Temporal variation of oxidant stress in critically ill patients


Gunaydin B., Sancak B., Candan S., Sariahmetoglu M., Ozcagli G., Tunctan B., ...More

MINERVA ANESTESIOLOGICA, vol.73, no.5, pp.261-266, 2007 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 5
  • Publication Date: 2007
  • Journal Name: MINERVA ANESTESIOLOGICA
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.261-266

Abstract

Aim. Our aim was to investigate indicators of lipid peroxidation via observing temporal changes or daily fluctuations in cytoprotective enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX), and serum components possessing antioxidant activity against free radicals and malondialdehyde (MDA) such as uric acid. This study was conducted in a small number of critically ill patients versus healthy volunteers in order to design an effective antioxidant therapy regimen under oxidative stress.