Enhancement of heat transfer to the fluid can be done by turbulence promoters such as attached fins to the pipe walls. In this study, the flow field and the heat transfer rates were numerically investigated in a pipe with an internally attached fin. Numerical simulations were conducted for four different types of fluids and for different fin heights and locations, and as the Reynolds number was varied, the effects of the fin on Nusselt number and friction factors were investigated. For all the Reynolds numbers considered in this study, the effect of fin location on the heat transfer rate and friction factor was negligible. As the fin height was increased, the mean Nusselt number and the friction factor also increased in the turbulent flow regimes. For low Prandtl number fluids (Pr = 0.011), the main heat transfer mode is conduction, and hence the mean Nusselt number slightly affected the flow rates.