Effects of Scaling and Root Planing and Subantimicrobial Dose Doxycycline on Gingival Crevicular Fluid Levels of Matrix Metalloproteinase-8, -13 and Serum Levels of HsCRP in Patients With Chronic Periodontitis

TÜTER G., SERDAR M. A., Kurtis B., Walker S. G., Atak A., Toyman U., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.81, sa.8, ss.1132-1139, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 81 Sayı: 8
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1902/jop.2010.090694
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1132-1139
  • Anahtar Kelimeler: C-reactive protein, doxycycline, gingival crevicular fluid, matrix metalloproteinases, periodontitis, treatment, C-REACTIVE PROTEIN, ADULT PERIODONTITIS, CLINICAL-PARAMETERS, THERAPY, DISEASE, MARKERS, TISSUE, INHIBITOR, INFLAMMATION, PREVENTION
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: This study evaluates the efficacy of subanti-microbial dose doxycycline (SDD) in conjunction with scaling and root planing (SRP) on gingival crevicular fluid (GCF) levels of matrix metalloproteinase (MMP)-8 and -13 and on serum levels of high-sensitivity C-reactive protein (HsCRP) in patients with chronic periodontitis (CP).