Effects of Scaling and Root Planing and Subantimicrobial Dose Doxycycline on Gingival Crevicular Fluid Levels of Matrix Metalloproteinase-8, -13 and Serum Levels of HsCRP in Patients With Chronic Periodontitis

TÜTER, GÜLAY; SERDAR, Muhittin; Kurtis, MAZLUM; Walker, Stephen; Atak, AYŞEGÜL; Toyman, Utku; Pinar, Selin; Aykan, Tuba

doi:10.1902/jop.2010.090694

Effects of Scaling and Root Planing and Subantimicrobial Dose Doxycycline on Gingival Crevicular Fluid Levels of Matrix Metalloproteinase-8, -13 and Serum Levels of HsCRP in Patients With Chronic Periodontitis

TÜTER G., SERDAR M. A., Kurtis B., Walker S. G., Atak A., Toyman U., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.81, sa.8, ss.1132-1139, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 81 Sayı: 8
Basım Tarihi: 2010
Doi Numarası: 10.1902/jop.2010.090694
Dergi Adı: JOURNAL OF PERIODONTOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1132-1139
Anahtar Kelimeler: C-reactive protein, doxycycline, gingival crevicular fluid, matrix metalloproteinases, periodontitis, treatment, C-REACTIVE PROTEIN, ADULT PERIODONTITIS, CLINICAL-PARAMETERS, THERAPY, DISEASE, MARKERS, TISSUE, INHIBITOR, INFLAMMATION, PREVENTION
Gazi Üniversitesi Adresli: Evet

Özet

Background: This study evaluates the efficacy of subanti-microbial dose doxycycline (SDD) in conjunction with scaling and root planing (SRP) on gingival crevicular fluid (GCF) levels of matrix metalloproteinase (MMP)-8 and -13 and on serum levels of high-sensitivity C-reactive protein (HsCRP) in patients with chronic periodontitis (CP).