Cardiovascular Drug Therapy for Human Newborn: Review of Pharmacodynamic Data

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Ergenekon E., Rojas-Anaya H., Bravo M. C., Kotidis C., Mahoney L., Rabe H.

CURRENT PHARMACEUTICAL DESIGN, vol.23, no.38, pp.5850-5860, 2017 (SCI-Expanded)

• Publication Type: Article / Review
• Volume: 23 Issue: 38
• Publication Date: 2017
• Doi Number: 10.2174/1381612823666170918122755
• Journal Name: CURRENT PHARMACEUTICAL DESIGN
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.5850-5860
• Gazi University Affiliated: Yes

Abstract

Background: Circulatory failure in preterm and term newborn infants is commonly treated with inotropes or vasoactive medications. In this structured literature review, the available data on pharmacodynamic effects of the inotropes adrenaline, dobutamine, dopamine, levosimendan, milrinone, noradrenaline, and the vasoactive drugs vasopressin and hydrocortisone are presented.