The effects of melatonin on brain nitrosative stress and energy balance in fructose-mediated metabolic syndrome model

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OZAN G., Bircan F. S., Topal T., Turkozkan N.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.41, no.1, pp.37-43, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 41 Issue: 1
• Publication Date: 2016
• Doi Number: 10.1515/tjb-2016-0006
• Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.37-43
• Gazi University Affiliated: Yes

Abstract

Objective: Metabolic syndrome (MetS), one of the common health problems seen with increasing frequency in today's modern societies, is also a important risk factor for neurological disorders such as stroke, depression, Alzheimer's disease. On the other hand, melatonin is a neurohormone, has potent antioxidant and neuroprotective activities. In the present study, we aimed to investigate the possible protective effects of melatonin administration on brain tissue in fructose-mediated MetS model.