JOURNAL OF SURGICAL RESEARCH, cilt.184, ss.422-429, 2013 (SCI İndekslerine Giren Dergi)
Background: Hemorrhagic shock is a leading cause of death following severe trauma, and platelet transfusions are frequently necessary to achieve hemostasis. Platelets, however, require special storage conditions, and storage time has been associated with loss of platelet quality. We hypothesized that standard storage conditions have a deleterious effect on platelet mitochondrial function and platelet activation.