Two oleanene glycosides from the aerial parts of Caltha polypetala

Baykal T., Bedir E., Calis I., Aquino R., Piacente S., Pizza C.

PHYTOCHEMISTRY, vol.51, no.8, pp.1059-1063, 1999 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 8
  • Publication Date: 1999
  • Doi Number: 10.1016/s0031-9422(99)00164-8
  • Journal Name: PHYTOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1059-1063
  • Gazi University Affiliated: No

Abstract

Two new oleanene glycosides (1-2) possessing hederagenin as the aglycone were isolated from the methanolic extract of the aerial parts of Caltha polypetala together with four known glycosides. The saccharide portion linked to C-3 of the aglycone is made up of alpha-L-arabinopyranose, alpha-L-rhamnopyranose and galactopyranose in the new compounds; while compound 1 possesses linked to C-28 a trisaccharide moiety made up of two beta-D-glucopyranose and one alpha-L-rhamnopyranose unit, in compound 2 the 28-COOH group is free. The structures were elucidated by 1D and 2D NMR experiments including H-1-H-1 (DQF-COSY, 1D-TOCSY, 2D-ROESY) and H-1-C-13 (HSQC, HMBC) spectroscopy. (C) 1999 Elsevier Science Ltd. All rights reserved.