Two oleanene glycosides from the aerial parts of Caltha polypetala

Baykal T., Bedir E., Calis I., Aquino R., Piacente S., Pizza C.

PHYTOCHEMISTRY, cilt.51, sa.8, ss.1059-1063, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 8
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0031-9422(99)00164-8
  • Dergi Adı: PHYTOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1059-1063
  • Gazi Üniversitesi Adresli: Hayır

Özet

Two new oleanene glycosides (1-2) possessing hederagenin as the aglycone were isolated from the methanolic extract of the aerial parts of Caltha polypetala together with four known glycosides. The saccharide portion linked to C-3 of the aglycone is made up of alpha-L-arabinopyranose, alpha-L-rhamnopyranose and galactopyranose in the new compounds; while compound 1 possesses linked to C-28 a trisaccharide moiety made up of two beta-D-glucopyranose and one alpha-L-rhamnopyranose unit, in compound 2 the 28-COOH group is free. The structures were elucidated by 1D and 2D NMR experiments including H-1-H-1 (DQF-COSY, 1D-TOCSY, 2D-ROESY) and H-1-C-13 (HSQC, HMBC) spectroscopy. (C) 1999 Elsevier Science Ltd. All rights reserved.