JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, cilt.19, sa.1, ss.112-113, 2005 (SCI-Expanded)
The most commonly reported side-effects of recombinant interferon-1betaa and 1b include local inflammatory injection site reactions, headache, fever, myalgia and a flu-like syndrome. In this case report, we describe the occurrence of cutaneous necrosis and dermal fibrosis following intramuscular interferon-pla injections in a multiple sclerosis patient.