MINI-REVIEWS IN MEDICINAL CHEMISTRY, cilt.18, sa.8, ss.711-716, 2018 (SCI-Expanded)
Background: Cholinesterase family consists of two sister enzymes; acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) which hydrolyze acetylcholine. Since deficit of acetylcholine has been evidenced in patients of Alzheimer's disease (AD), cholinesterase inhibitors are currently the most prescribed drugs for the treatment of AD.