Expression of Podocyte Related Proteins and TGF-beta 1, WT-1 in Minimal Change Disease and Focal Segmental Glomerulosclerosis


Tatli Dogan H., IŞIK GÖNÜL İ. , Karakan S., Dogan M., Memis L.

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.27, no.3, pp.293-301, 2018 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.5262/tndt.2018.3273
  • Title of Journal : TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
  • Page Numbers: pp.293-301

Abstract

OBJECTIVE: Focal segmental glomerulosclerosis and minimal change disease are primary renal diseases representing with proteinuria. Following the identification of the role of podocyte-related molecules in the glomerular filtration barrier and the detection of the pivotal role of nephrin in the development of congenital nephrotic syndrome, the assessment and expression profiles of these proteins in acquired nephrotic syndrome have also come into question.