COVID-19 infection is mainly spread by droplets and contact routes. In aerosol generating processes such as intubation and mask ventilation, the contamination risk of COVID-19 is greatly increased. It is important to use PPE during hospital care or outpatient services in the COVID-19 pandemic. Due to its frequent and necessary use during pandemic, PPE deficiency is an important problem worldwide. To prevent this problem, current information about optimal PPE use in hospitals has been evaluated. In this review, the correct use of PPE and reuse conditions of the same PPE are discussed. In addition, about the requirements and conditions of use of PPE health practices in Turkey were compiled.