Are orthobiologics the next chapter in clinical orthopedics? A literature review

Sezgin E. A., Atik O. S.

EKLEM HASTALIKLARI VE CERRAHISI-JOINT DISEASES AND RELATED SURGERY, cilt.29, sa.2, ss.110-116, 2018 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5606/ehc.2018.005
  • Dergi Adı: EKLEM HASTALIKLARI VE CERRAHISI-JOINT DISEASES AND RELATED SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.110-116
  • Anahtar Kelimeler: Augmentation, bone morphogenic protein, bone, cartilage, ligament, orthobiologics, platelet-rich plasma, PLATELET-RICH PLASMA, AUTOLOGOUS CHONDROCYTE IMPLANTATION, BONE MORPHOGENETIC PROTEIN-2, CARTILAGE DEFECTS, ZOLEDRONIC ACID, LIGAMENT, GRAFTS, MOSAICPLASTY, AUGMENTATION, RESORPTION
  • Gazi Üniversitesi Adresli: Evet

Özet

Orthobiologics are biologically derived materials which aim to promote healing and regeneration of tissues that are the focus of orthopedic surgery. Since bones, ligaments, tendons, and cartilage have different healing and regeneration characteristics, treatment strategies and clinical problems related to these tissues greatly differ. Although orthobiolgics are an old concept, most of the advancements in this field have been accomplished within the last two decades. A large number of promising laboratory studies show that orthobiolics hold a great potential in launching the next chapter of orthopedics. In this article, the use, research on this subject, future potential of orthobiologics, and the tissues in focus have been briefly reviewed.