Effects of Gamma Knife Radiosurgery on Optic Pathways in Sellar Tumor Patients: Voxel-based and Tract-based DTI Analysis

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Arıkan B., Yazol M., Bhuiyan E., Emmez Ö. H., Zhou X. J., Öner A. Y., ...Daha Fazla

ISMRM & ISMRT Yıllık Toplantısı (2025), Hawaii, Amerika Birleşik Devletleri, 10 - 15 Haziran 2025, cilt.33, ss.1-3, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 33
  • Basıldığı Şehir: Hawaii
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Sayfa Sayıları: ss.1-3
  • Gazi Üniversitesi Adresli: Evet

Özet

Keywords: Tumors (Post-Treatment), Tumors, brain tumor, gamma knife radiosurgery, assessment of treatment toxicity, optic pathways

Motivation: Gamma Knife radiosurgery (GKRS) for sellar tumors risks radiation exposure to critical optic pathways. This study investigates the possible GKRS-induced microstructural changes and thereby assessing treatment toxicity.

Goal(s): Gamma Knife radiosurgery (GKRS) for sellar tumors risks radiation exposure to critical optic pathways. This study investigates the possible GKRS-induced microstructural changes and thereby assessing treatment toxicity.

Approach: Gamma Knife radiosurgery (GKRS) for sellar tumors risks radiation exposure to critical optic pathways. This study investigates the possible GKRS-induced microstructural changes and thereby assessing treatment toxicity.

Results: TBSS and VBA analyses showed no significant microstructural changes in multiple DTI parameters within the optic radiation.

Impact: Advanced DTI analysis with TBSS and VBA confirms that GKRS preserves optic radiation integrity in sellar tumor patients. Future studies can extend these methods to assessing long-term radiation effects on neural pathways and refining neuroprotective strategies in radiotherapy.