The periodic table is an introduction to the elements and is important in terms of chemistry education. In many chemistry teaching programs around the world, effective use of periodic table is aimed. However, considering the characteristics of the periodic table, it is not possible to encounter with a way or a method to use them in the literature. For this reason, the aim of this study is to draw attention to the nature of the periodic table, and to open a door to think that this nature is advantageous in terms of chemistry education. For this purpose, the historical development and present situation of the periodic table are briefly mentioned and the concepts of periodic law, periodic system and periodic table are analyzed from a philosophical point of view. Afterwards, in the light of the methodological and epistemological aspects of the historical development of the periodic table, periodic law and periodic system relations is discussed in the context of the chemistry education for the effective use of periodic table. In this discussion, the hypothetical-deductive method was pointed that might be compatible for the effective use of the periodic system, and some suggestions for chemistry education have been given.