New aryldisulfonamides were synthesized and characterized by FTIR, H-1 NMR, C-13 NMR, HETCOR, COSY, LC-MS and elemental analysis techniques. The compounds gave intense emissions, where lambda(max) = 405, 379 and 402 nm, upon irradiation by Ultra-Violet light. The photoluminescence quantum yields and long excited-state lifetimes of the compounds were calculated and were found to have photoluminescence quantum yields 39 +/- 1.8%, 45 +/- 2.2% and 34 +/- 1.4% and long excited-state lifetimes of 3.65 +/- 0.16, 4.17 +/- 0.20 and 3.15 +/- 0.12 ns, respectively. The photoluminescence intensities and quantum yields of compounds varied with the position of substituent on the ring and the chain length between aromatic rings. These novel compounds may be of interest as organic emitting materials for electroluminescent devices. The visible absorption maxima were calculated using time-depended density-functional theory (ID-OFT) and Zerner's intermediate neglect of differential overlap/spectroscopic (ZINDO/S) method in the gas phase. Further, the compounds were evaluated for in vitro antimicrobial activity against various microorganisms by microdilution and disk diffusion methods. (C) 2011 Elsevier B.V. All rights reserved.