Safety tests on mice and Guinea-Pigs with Bacillus thuringiensis israilensis(PubMed)

Özer A. N., Yörükhan S., Çakmakçı L., Boşgelmez A., Alten S. B., Gürkan B., ...More

Journal of Islamic Academy of Sciences, vol.3, no.1, pp.41-48, 1990 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 3 Issue: 1
  • Publication Date: 1990
  • Journal Name: Journal of Islamic Academy of Sciences
  • Journal Indexes: Sobiad Atıf Dizini
  • Page Numbers: pp.41-48
  • Gazi University Affiliated: No


Mammalian toxicity tests were carried out on mice and guinea-pigs with Bacillus thuringiensis israelensis number 330211, isolated from the Icel region of Turkey. Test animals were injected by various routes including subcutaneous intraperitoneal, intravenous, oral, percutaneous, inhalation and eye irritation test, using stock suspension of 2X108 per/ml bacteria for each inoculation. None of the animals showed any evidence of illness and behaviour, growth, average organ and body weights were normal. Key Words: Safety tests, mice, guinea-pig, biological control, Bacillus thuringiensis israelensis.