The pharmacokinetics and effects of diltiazem in rabbits

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Oruc S., Orhan D., Orhan M., Irkec M., Basci N., Barun S., ...More

EUROPEAN JOURNAL OF OPHTHALMOLOGY, vol.10, no.1, pp.46-50, 2000 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 10 Issue: 1
• Publication Date: 2000
• Doi Number: 10.1177/112067210001000108
• Journal Name: EUROPEAN JOURNAL OF OPHTHALMOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.46-50
• Keywords: glaucoma, diltiazem, histopathology, high-performance liquid chromatography, GLAUCOMA FILTERING SURGERY, CALCIUM-CHANNEL BLOCKERS, OPEN-ANGLE GLAUCOMA, MITOMYCIN-C, POSTOPERATIVE 5-FLUOROURACIL, LOW-TENSION, COMPLICATIONS, TRABECULECTOMY, DEXAMETHASONE, MANAGEMENT
• Gazi University Affiliated: No

Abstract

PURPOSE. To investigate the effect of diltiazem on wound healing after the creation of conjunctival flaps in rabbit eyes. Also, to investigate the pharmacokinetics of diltiazem in rabbits after subconjunctival and topical administration.