In high-performance military aircraft, high centrifugal forces result in sharp turns and such emergency maneuvers significantly affect the pilot's physiological condition and performance. The human centrifuge system is a dynamic flight simulator used to generate artificial G forces realistically. One of the objectives of this study is to underline the significance of system safety of human centrifuge systems. System safety should be considered well during the system design to prevent possible problems during training. Failure mode and effects analysis is suggested for making the system reliable.