Bale's concentric sclerosis - Report of two patients with magnetic resonance imaging follow-up

Bolay H. B. , Karabudak R., Tacal T., Onol B., Selekler K., Saribas O.

JOURNAL OF NEUROIMAGING, vol.6, no.2, pp.98-103, 1996 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 2
  • Publication Date: 1996
  • Doi Number: 10.1111/jon19966298
  • Title of Journal : JOURNAL OF NEUROIMAGING
  • Page Numbers: pp.98-103


Balo's concentric sclerosis was diagnosed antemortem in 2 patients, by magnetic resonance (MR) imaging showing striking concentric alternating rings in 1 patient and by characteristic histopathological features in the other. The course of the lesions and the concentric pattern were followed by MR imaging for 3 years and 18 months, respectively. One patient demonstrated spontaneous remission that has not been reported in Bale's disease. Bale's disease may not have a fulminant course as described in the past and the MR appearance of the chronic lesion may resemble that of a chronic multiple sclerosis plaque.