Protective effects of Nigella sativa oil against carboplatin-induced liver damage in rats

Erisgin, Zuleyha; ATASEVER, MELAHAT; Cetinkaya, Kadir; AKARCA DİZAKAR, SAADET; ÖMEROĞLU, SUNA; ŞAHİN, HÜSEYİN

doi:10.1016/j.biopha.2018.12.037

Protective effects of Nigella sativa oil against carboplatin-induced liver damage in rats

Erisgin Z., ATASEVER M., Cetinkaya K., AKARCA DİZAKAR S. Ö., ÖMEROĞLU S., ŞAHİN H.

BIOMEDICINE & PHARMACOTHERAPY, cilt.110, ss.742-747, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 110
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.biopha.2018.12.037
Dergi Adı: BIOMEDICINE & PHARMACOTHERAPY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.742-747
Anahtar Kelimeler: Apoptosis, Carboplatin, Nigella sativa, Gas chromatography, Liver, Rat, INDUCED HEPATOTOXICITY, THYMOQUINONE, INTRAPERITONEAL, CHEMOTHERAPY, TOXICITY, INJURY, STRESS, MODEL
Gazi Üniversitesi Adresli: Evet

Özet

Objective: This study aimed to investigate the protective effects of nigella saliva oil (NSO) against liver damage due to intraperitoneal (i.p.) usage of carboplatin which is commonly used as a chemotherapeutic agent.