The Evaluation of Epigallocatechin Gallate and N-Acetylcysteine on Serum Testosterone Levels in Male Guinea Pigs Expose to Cell Phone Microwave

KISMALI G., ÖZGÜR BÜYÜKATALAY E. , Sayiner S., Alpaslan B., GÜLER ÖZTÜRK G. , Seyhan N., ...More

JOURNAL OF ANIMAL AND VETERINARY ADVANCES, vol.8, no.6, pp.1149-1151, 2009 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 6
  • Publication Date: 2009
  • Page Numbers: pp.1149-1151


Recently, there has been a few information on the effects of mobile phone-exposed on reproduction. The aim of this study to determine the effects of antioxidants namely EGCG and NAC on the serum testosteron levels in the cell phone-exposed guinea pigs. Three-months-old mate Guinea pigs were randomized into 6 groups; sham group, not exposed to mobile phone, NAC administration group (300 mg kg(-1) i.p. during 7 days), 20 min mobile phone-exposed group with NAC administration, 20 min mobile phone-exposed group, EGCG administration group (25 mg kg(-1) i.p. during 7 days) and 20 min mobile phone-exposed group with EGCG administration. During the exposure of every guinea pig, external E fields were measured by NARDA EMR 300 and type 8.3 probe. Guinea pigs were exposed to RFR averaged as 11.2 +/- 0.5 V m(-1) for 20 min a day during 7 days. Serum testosterone levels were analysed by ELISA. The serum testosterone levels were found insignificantly increased in mobile phone-exposed group compared to the control and the other groups (p>0.05). Likewise, the serum testosterone levels were not found significantly different in the N-Acetyl L-Cysteine (NAC) and Epigallocatechin Gallate (EGCG) administrated groups compared to the sham group.