Membranous nephropathy in a patient with ankylosing spondylitis: A rare renal manifestation or just a coincidence?


Tohma E. K., GÖĞÜŞ F. N.

Turkish Journal of Physical Medicine and Rehabilitation, cilt.69, sa.2, ss.244-247, 2023 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5606/tftrd.2023.8801
  • Dergi Adı: Turkish Journal of Physical Medicine and Rehabilitation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.244-247
  • Anahtar Kelimeler: Ankylosing spondylitis, glomerulonephritis, membranous nephropathy, nephrotic syndrome, proteinuria, spondyloarthritis
  • Gazi Üniversitesi Adresli: Evet

Özet

Renal involvement in ankylosing spondylitis (AS) is uncommon and usually secondary to amyloidosis or analgesic nephropathy. A 41-year-old female patient who was diagnosed with human leukocyte antigen-B27-positive AS 16 years ago was admitted to the rheumatology outpatient clinic with pretibial and pedal edema. She had nephrotic-range proteinuria. Renal biopsy findings confirmed the diagnosis of membranous nephropathy. Extensive malignancy evaluation was negative. Edema regressed, renal functions stabilized, and proteinuria reduced within two months after immunosuppressive therapy.