The relationship between vascular endothelial growth factor (VEGF) and microalbuminuria in patients with essential hypertension


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Ebinc F. A. , Haksun E., Ulver D. B. , Koc E., ERTEN Y. , ALTOK K. , ...More

INTERNAL MEDICINE, vol.47, no.17, pp.1511-1516, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 17
  • Publication Date: 2008
  • Doi Number: 10.2169/internalmedicine.47.1122
  • Title of Journal : INTERNAL MEDICINE
  • Page Numbers: pp.1511-1516

Abstract

Objective The existence of microalbuminuria (MAU) in patients with essential hypertension is a strong indicator of microvascular damage. Although endothelial dysfunction and increased vascular permeability both have a role in the development of MAU, its ethiopathogenesis in hypertensive patients is not yet clearly understood. Vascular endothelial growth factor (VEGF) is the most important regulator of pathological or physiological angiogenesis and it additionally leads to increased vascular permeability. This study aims to assess the relationship of serum VEGF levels to MAU in non-complicated, newly-diagnosed essential hypertensive patients (EHs).