Effect of Fullerenol C60 on Erythrocyte Deformability During Ischaemia-Reperfusion Injury of Lower Extremity in Diabetic Rats


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KİP G. , Kartal H., Comu F. M. , Polat Y., ARSLAN M. , KÜÇÜK A.

GAZI MEDICAL JOURNAL, cilt.30, sa.4, ss.374-377, 2019 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Konu: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.12996/gmj.2019.96
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Sayfa Sayıları: ss.374-377

Özet

Background: Fullerenol, a water-soluble C60-fullerene derivative synthesized by Chiang et al, has been demonstrated to be able to scavenge free radicals in vitro and in vivo. Although its protective effects have been already studied and shown in ischemia reperfusion (IR) injury, additional investigation is necessary for its effect on erythrocyte deformability. The purpose of our study was to look into the effects of fullerenol C60 on erythrocyte deformability in rat lower extremity ischemia reperfusion injury model.