This research was conducted to examine the correlation between depression and hopelessness levels in mothers of disabled children between the ages 5 and 7. A total of 126 mothers of children with disabilities was used in the study. They were obtained from the nursery schools of the First Education Schools of the Ministry of Education or from private schools. In this study the Beck Depression Scale (Beck, Ward, Mendelson, Mock, & Erbaugh, 1961), Beck Hopelessness Scale (Beck, Lester, & Trexler, 1974) and a General Information Form (Ceylan & Aral, 2005) were used for statistical analyses. The findings suggested a significant correlation between the depression and hopelessness levels of mothers of disabled children (P < .01).