Prognostic Factors and Long-Term Outcome in 52 Turkish Children With Hemophagocytic Lymphohistiocytosis.

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Kaya Z., Bay A., Albayrak M., Kocak U., Yenicesu I., Gursel T.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, vol.16, no.6, 2015 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 16 Issue: 6
• Publication Date: 2015
• Doi Number: 10.1097/pcc.0000000000000449
• Journal Name: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Keywords: children, hemophagocytic syndrome, prognosis, STEM-CELL TRANSPLANTATION, DISSEMINATED INTRAVASCULAR COAGULATION, LYSINURIC PROTEIN INTOLERANCE, RISK-FACTORS, MUTATIONS, PRESENTATIONS, SYNTAXIN-11, GUIDELINES, PHENOTYPES, INFECTION
• Gazi University Affiliated: Yes

Abstract

Objectives: Hemophagocytic lymphohistiocytosis is a syndrome of pathologic immune activation that shares similar clinical and laboratory phenotypes with severe sepsis. Recent studies led to better recognition of hemophagocytic lymphohistiocytosis by clinicians, but no consensus exists on the criteria for high-risk patients.