Harris Platelet Syndrome in Patients of Non-Indian Origin

ASLAN D.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.38, sa.8, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 8
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1097/mph.0000000000000602
  • Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Harris platelet syndrome, congenital thrombocytopenia, Turkish patients, ASYMPTOMATIC CONSTITUTIONAL MACROTHROMBOCYTOPENIA
  • Gazi Üniversitesi Adresli: Evet

Özet

Inherited giant platelet disorders are a subgroup of congenital thrombocytopenias characterized by decreased platelet counts along with macroplatelets and variable bleeding symptoms. Harris platelet syndrome, a newly described rare entity, is a subtype of inherited giant platelet disorders and is characterized by mild-to-severe thrombocytopenia, macroplatelets, and no bleeding manifestations. This entity was observed incidentally in healthy blood donors from India in the early 2000s, and the reported cases to date have without exception originated from the same region of the Indian subcontinent. We herein report the occurrence of Harris platelet syndrome in patients from a different ethnogeographic origin.