(2-Benzylidenehydrazino) benzoxazole derivatives, synthesis and antifungal activities
Gazi Universitesi Eczacilik Fakultesi Dergisi, cilt.12, sa.2, ss.103-111, 1995 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 2
- Basım Tarihi: 1995
- Dergi Adı: Gazi Universitesi Eczacilik Fakultesi Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.103-111
- Anahtar Kelimeler: 2-hydrazinobenzoxazole, antifungal activity, arylaldehydehydrazone
- Gazi Üniversitesi Adresli: Evet
Özet
Benzoxazole-2-thione as the starting material has been synthesized, and 2-methylthiobenzoxazole has been obtained therefrom. 2-Hydrazinobenzoxazole has been prepared from 2-methylthiobenzoxazole by heating with hydrazine hydrate under pressure in ethanol. Substituted arylhydrazones have been synthesized by the reaction of 2-hydrazinobenzoxazole with o- or p-substituted arylaldehydes, and antifungal activities of the synthesized compounds have been tested against yeast-like fungi such as Candida albicans, Candida stellatoidea, Candida parapsilosis, Candida pseudotropicalis.