The effects of topical granulocyte-macrophage colony-stimulating factor on dural healing in rats after induced cerebrospinal. fluid leakage

Kurt G., Boercek A. Ö., Cemil B., Ucankus N. L., Dogulu F., Baykaner M. K.

JOURNAL OF NEUROSURGERY-SPINE, cilt.7, sa.4, ss.419-422, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 4
  • Basım Tarihi: 2007
  • Doi Numarası: 10.3171/spi-07/10/419
  • Dergi Adı: JOURNAL OF NEUROSURGERY-SPINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.419-422
  • Gazi Üniversitesi Adresli: Evet

Özet

Object. Dural defects must be repaired to protect the central nervous system from contamination. Although there are various experimental and commercial substances available for this purpose, the ultimate method of watertight dural closure has yet to be discovered. In this study, the authors investigate the effects of topically applied recombinant mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) on dural healing in a rat model of dural injury and cerebrospinal fluid leakage.