Continuous venovenous hemodiafiltration in the treatment of newborns with an inborn metabolic disease: a single center experience


Akduman H., OKULU E., EMİNOĞLU F. T. , KENDİRLİ T., TUNÇ G., Azapagasi E. , ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.50, no.1, pp.12-17, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.3906/sag-1811-8
  • Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.12-17
  • Keywords: Inborn metabolic diseases, renal replacement therapy, continuous venovenous hemodiafiltration, newborn, survival, RENAL REPLACEMENT THERAPY, CONTINUOUS ARTERIOVENOUS HEMOFILTRATION, PERITONEAL-DIALYSIS, ERRORS, CHILDREN, HYPERAMMONEMIA, HEMODIALYSIS, MANAGEMENT, FAILURE, THROMBOCYTOPENIA

Abstract

Background/aim: Most inborn metabolic diseases are diagnosed during the neonatal period. The accumulation of toxic metabolites may cause acute metabolic crisis with long-term neurological dysfunction and death. Renal replacement therapy (RRT) modalities allow the efficient removal of toxic metabolites. In this study, we reviewed our experience with continuous venovenous hemodiafiltration (CVVHDF) as RRT for newborns with an inborn metabolic disease.