A comprehensive morphological study for basal-like breast carcinomas with comparison to nonbasal-like carcinomas


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Cakir A., IŞIK GÖNÜL İ., Uluoglu O.

DIAGNOSTIC PATHOLOGY, vol.7, 2012 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7
  • Publication Date: 2012
  • Doi Number: 10.1186/1746-1596-7-145
  • Journal Name: DIAGNOSTIC PATHOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Keywords: Basal-like breast carcinoma, Breast, Breast carcinoma, Morphology, GROWTH-FACTOR RECEPTOR, INVASIVE DUCTAL CARCINOMA, IN-SITU, MOLECULAR SUBTYPES, CANCER SUBTYPES, POOR-PROGNOSIS, EXPRESSION, PHENOTYPE, FEATURES, IMMUNOHISTOCHEMISTRY

Abstract

Background: Breast carcinomas can be classified into five subtypes based on gene expression profiling or immunohistochemical characteristics. Among these subtypes, basal-like breast carcinomas (BLBCs) are one of the most studied group, due to their poor prognosis. The aim of this study was to investigate the prevalance, morphological and immunohistochemical features of BLBCs, in Turkish population.