Investigation of gamma knife radiosurgical treatment effect on optic pathways in using diffusion tensor MRI

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YAZOL M., ÖZER H., BARUTCU B., KURT G., EMMEZ Ö. H., ÖNER A. Y.

Türk Nöroradyoloji Derneği 31. Yıl Uluslararası Katılımlı Tanısal ve Girişimsel Nöroradyoloji, Baş-Boyun Radyolojisi Kongresi, İstanbul, Türkiye, 18 Şubat 2022, cilt.64, ss.399-422 identifier identifier identifier

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 64
  • Doi Numarası: 10.1007/s00234-021-02887-5
  • Basıldığı Şehir: İstanbul
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.399-422
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: To investigate DTI indices changes of the early

radiation-induced effects on optic pathways that occur after

GKRS for sellar-parasellar tumors.

Materials and methods: Twenty-five patients who received

Gamma Knife stereotactic radiosurgery for sellar- parasellar

tumors were included in the study. Each patient underwent

MRI with T1WI, DTI, and T2WI before and at the 3 months

after radiosurgery. The regions of interest (ROIs) were set

on each optic nerve (ON), anterior-central and posterior

optic radiations (OR), and control localization. For each

ROI, fractional anisotropy (FA), apparent diffusion coefficient

(ADC) axial diffusivity (AD), radial diffusivity (RD),

eigenvalues were calculated. Pre and post-radiosurgery differences

of DTI values were statistically compared by using

paired t-test