EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, vol.40, no.2, pp.213-227, 2013 (Peer-Reviewed Journal)
Article / Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Science Citation Index Expanded, Scopus
Dopamine transporter, Gender difference, Age effects, SPECT, Scatter correction, Database, PARKINSONS-DISEASE, DOPAMINE TRANSPORTERS, I-123-FP-CIT SPECT, BRAIN, PREVALENCE, NEUROTRANSMISSION, PROGRESSION, DIAGNOSIS, LEVODOPA, DECLINE
Dopamine transporter (DAT) imaging with [I-123]FP-CIT (DaTSCAN) is an established diagnostic tool in parkinsonism and dementia. Although qualitative assessment criteria are available, DAT quantification is important for research and for completion of a diagnostic evaluation. One critical aspect of quantification is the availability of normative data, considering possible age and gender effects on DAT availability. The aim of the European Normal Control Database of DaTSCAN (ENC-DAT) study was to generate a large database of [I-123]FP-CIT SPECT scans in healthy controls.