Drug-drug interactions in patients using tyrosine kinase inhibitors: A multicenter retrospective study

Ergun Y., Ozdemir N. Y., Toptas S., Kurtipek A., Eren T., Yazic O., ...Daha Fazla

JOURNAL OF BUON, cilt.24, sa.4, ss.1719-1726, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 4
  • Basım Tarihi: 2019
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1719-1726
  • Anahtar Kelimeler: tyrosine kinase inhibitors, drug-drug interactions, antibiotics, proton pump inhibitors, cancer, CANCER-PATIENTS, P-GP, ABSORPTION, PHARMACOKINETICS, KETOCONAZOLE, PREVALENCE, MEDICATION, METABOLISM, PAZOPANIB, AGENTS
  • Gazi Üniversitesi Adresli: Evet

Özet

Purpose: Tyrosine kinase inhibitors (TKIs) are frequently used drugs in oncology practice. Although oral administration is an advantage, long-term use increases potential drug-drug interaction risk. The purpose of this study was to assess the prevalence of potential TKI-drug interaction (PTDI) in patients who used TKIs and increase awareness of this subject.