Endometriosis is an estrogen-dependent diseases associated with pain and infertility with features of most frequently symptoms according chronic inflammation, dysmenorrhoea, deep dyspareunia, dyschezia and dysuria. Functional endometrial and stromal tissue implants exist outside the uterine cavity and causes inflammatory processes. Therefore, several undesirable reactions can occur. There are several diagnostic methods however histopathology is one of the gold standards. This review summarizes the histopathological indications of endometriosis disease with different researches.