Uluslararası Katılımlı Türk Romatoloji Kongresi 8-12 Mart 2023, , Antalya, Türkiye, 8 - 12 Mart 2023, ss.59
Objective—To assess neurological soft signs (NSS) in individuals with fibromyalgia
syndrome (FMS) and to evaluate its relationship with disease severity.
Methods—Patients with FMS (n=30) and healthy controls (n=30) underwent systematic
neurological examination and assessment of NSS with Neurological Evaluation Scale (NES)
by a neurologist blinded to disease status. We obtained demographic and clinical data from
volunteers. Fibromyalgia Impact Questionnaire (FIQ) was used to determine impact of the
disease and Widespread Pain Index (WPI) and Symptom Severity Scale (SSS) were used to
determine disease severity in patients with FMS. We examined the correlation between NSS
and disease severity within the FMS group
Results—Compared to the control group, the FMS group had significantly more NSS total
score and scores of sequencing of complex motor acts (SCMA), sensory integration (SI),
motor coordination (MC) and other areas. FIQ and the disease duration of the FMS group
were not correlated with all of NES scores. WPI and SSS were correlated with NES total
score (p= 0,031 r= 0,394 p=0,026 r=0,406) and MC score (p= 0,042 r= 373 p=0,047 r=0,366)
but were not correlate scores of SCMA, SI and other areas.
Conclusions— This study shows that NSS are common in patients with FM, possibly due to
central sensitization and brain fokal gray matter abnormalities. The total NSS score correlated
with symptom severity but not correlated with the impact of disease in patients with FMS.