Adrenomedullin attenuates aortic cross-clamping induced myocardial injury in rats

Oyar, Eser; Kiris, Ilker; GÜLMEN, Şenol; Ceyhan, Betul; Cure, Medine; Sutcu, Recep; Lortlar, Nese; Okutan, Huseyin

doi:10.1016/j.amjsurg.2010.04.011

Adrenomedullin attenuates aortic cross-clamping induced myocardial injury in rats

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Oyar E. O., Kiris I., GÜLMEN Ş., Ceyhan B. M., Cure M. C., Sutcu R., ...More

AMERICAN JOURNAL OF SURGERY, vol.201, no.2, pp.226-232, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 201 Issue: 2
Publication Date: 2011
Doi Number: 10.1016/j.amjsurg.2010.04.011
Journal Name: AMERICAN JOURNAL OF SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.226-232
Keywords: Adrenomedullin, Abdominal aortic surgery, Ischemia-reperfusion, Myocardial injury, Oxidative stress, Caspase-3, Endothelin-1, Angiotensin II, INFLAMMATORY CYTOKINES, ISCHEMIA-REPERFUSION, ANEURYSM REPAIR, CYTOCHROME-C, RENAL INJURY, APOPTOSIS, RELEASE, CELLS, SYSTEM, SECRETION
Gazi University Affiliated: Yes

Abstract

BACKGROUND: In this study we investigate the effects of adrenomedullin on myocardial injury after ischemia-reperfusion (I/R) after abdominal aortic surgery.