Adrenomedullin attenuates aortic cross-clamping induced myocardial injury in rats


Oyar E. O. , Kiris I., GÜLMEN Ş., Ceyhan B. M. , Cure M. C. , Sutcu R., ...More

AMERICAN JOURNAL OF SURGERY, vol.201, no.2, pp.226-232, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 201 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.1016/j.amjsurg.2010.04.011
  • Title of Journal : AMERICAN JOURNAL OF SURGERY
  • Page Numbers: pp.226-232
  • Keywords: Adrenomedullin, Abdominal aortic surgery, Ischemia-reperfusion, Myocardial injury, Oxidative stress, Caspase-3, Endothelin-1, Angiotensin II, INFLAMMATORY CYTOKINES, ISCHEMIA-REPERFUSION, ANEURYSM REPAIR, CYTOCHROME-C, RENAL INJURY, APOPTOSIS, RELEASE, CELLS, SYSTEM, SECRETION

Abstract

BACKGROUND: In this study we investigate the effects of adrenomedullin on myocardial injury after ischemia-reperfusion (I/R) after abdominal aortic surgery.