Obesity is an independent prognostic factor of decreased pathological complete response to neoadjuvant chemotherapy in breast cancer patients

Karatas F., Erdem G. U., Sahin S., Aytekin A., YÜCE D., Sever A. R., ...More

BREAST, vol.32, pp.237-244, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32
  • Publication Date: 2017
  • Doi Number: 10.1016/j.breast.2016.05.013
  • Journal Name: BREAST
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.237-244
  • Keywords: Breast cancer, Neoadjuvant chemotherapy, Body mass index, Pathological complete response, Survival, BODY-MASS INDEX, HORMONE-RECEPTOR STATUS, COMPLETE ERADICATION, MOLECULAR SUBTYPES, INSULIN-RESISTANCE, PREDICTIVE FACTOR, POOLED ANALYSIS, SURFACE AREA, RISK-FACTORS, WEIGHT-GAIN
  • Gazi University Affiliated: Yes

Abstract

Purpose: The relation between higher body mass index (BMI) and pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer (BC) is a controversial issue according to the data of Western and Asian patients. The aim of this study is to evaluate BMI and pCR to NAC and discuss the importance of pCR outcomes in Turkish BC patients as a bridging country between Europe and Asia.