Radiological and Histopathological Comparison of Microporous Polysaccharide Hemospheres and Oxidized Regenerated Cellulose in the Rabbit Brain: A Study of Efficacy and Safety

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Emmez H., Tonge M., TOKGÖZ N., Durdag E., IŞIK GÖNÜL İ., Ceviker N.

TURKISH NEUROSURGERY, vol.20, no.4, pp.485-491, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.5137/1019-5149.jtn.3300-10.2
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.485-491
  • Keywords: Brain hemorrhage, Hemostasis, Magnetic resonance, Microporous polysaccharide hemospheres, Oxidized regenerated cellulose, TOPICAL HEMOSTATIC AGENTS, MODEL, COLLAGEN, INJURY, TUMOR
  • Gazi University Affiliated: Yes


AIM: Topical hemostatic agents are widely used in brain surgery but they have some disadvantages such as foreign body reaction, being a focus for infection and causing artifacts in radiological examinations. The purpose of this study is to compare the effectiveness and safety of microporous polysaccharide hemospheres (MPH) with a well known agent, oxidized regenerated cellulose (ORC), histopathologically and radiologically.