Akademik Veri Yönetim Sistemi
Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine, cilt.73, sa.1, ss.75-79, 2018 (SCI-Expanded)
Objectives: Patients with autoimmune gastritis may have symptoms suggestive of delayed gastric emptying. The aim of this study was to explore the predictive value of two scoring systems in the differentiation of delayed gastric emptying in patients with autoimmune gastritis. Methods: About 154 patients (106 women) with autoimmune gastritis whose gastric emptying test were available, were analyzed using two laboratory-based scoring systems: ‘global score’ (hemoglobin, mean corpuscular volume, gastrin, vitamin B12, and chromogranin A) and ‘simple score’ (hemoglobin, mean corpuscular volume, and gastrin) in order to discriminate delayed and normal gastric emptying. Results: The mean ‘simple score’ was 4.82 ± 0.94 for autoimmune gastritis patients with delayed gastric emptying and 0.72 ± 0.60 for patients with normal gastric emptying (p < 0.001). The mean ‘global score’ was 7.42 ± 0.81 for autoimmune gastritis patients with delayed gastric emptying and 1.176 ± 0.98 (p < 0.001) for patients with normal gastric emptying. There was also a positive correlation between severity of symptoms of patients with autoimmune gastritis and global (r = 0.83, p < 0.001) and simple scores (r = 0.81, p < 0.001). Conclusion: This model may help physicians, while evaluating autoimmune gastritis patients and deciding which patients need gastric emptying test. Gastric emptying study should be ordered in patients who are fulfilling the criteria proposed by these scoring systems.