Anti-ulcerogenic activity and isolation of the active principles from Sambucus ebulus L. leaves


YEŞİLADA E., GÜRBÜZ İ. , Toker G.

JOURNAL OF ETHNOPHARMACOLOGY, cilt.153, sa.2, ss.478-483, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 153 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.jep.2014.03.004
  • Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
  • Sayfa Sayıları: ss.478-483

Özet

Ethnopharmacological relevance: Sambucus ebulus L. has a very prominent place in Turkish folk medicine. Leaves of the plant are practiced externally to relieve rheumatic pain, to treat abscess, for wound healing and internally against hemorrhoids and stomachache. In a previous work, aqueous extract of the leaves was shown to possess potent antiulcerogenic activity on water immersion and immobilization-induced stress ulcer model in rats. This study aims to investigate the antiulcerogenic activity profile of the plant on various in vivo peptic ulcer models and gastric biochemical parameters and through bioassay-guided processing to isolate the active constituent (s) and to elucidate its structure.