Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas


ÇİÇİN İ., Ozatli T., Turkmen E., Ozturk T., Ozcelik M., ÇABUK D., ...More

BALKAN MEDICAL JOURNAL, vol.33, no.5, pp.517-524, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.5152/balkanmedj.2016.151268
  • Journal Name: BALKAN MEDICAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.517-524
  • Keywords: Carcinosarcoma, ovary, uterine, predictive factors, prognostic factors, MIXED MULLERIAN TUMOR, SURGICAL CYTOREDUCTION, ADJUVANT-THERAPY, STAGE-I, SURVIVAL, CHEMOTHERAPY, VARIABLES, SURGERY
  • Gazi University Affiliated: Yes

Abstract

Background: Prognostic factors and the standard treatment approach for gynaecological carcinosarcomas have not yet been clearly defined. Although carcinosarcomas are more aggressive than pure epithelial tumours, they are treated similarly. Serous/clear cell and endometrioid components may be predictive factors for the efficacy of adjuvant chemotherapy (CT) or radiotherapy (RT) or RT in patients with uterine and ovarian carcinosarcomas. Heterologous carcinosarcomas may benefit more from adjuvant CT.