The effect of radiofrequency radiation on DNA and lipid damage in non-pregnant and pregnant rabbits and their newborns


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GÜLER ÖZTÜRK G., TOMRUK A., Ozgur E., Seyhan N.

GENERAL PHYSIOLOGY AND BIOPHYSICS, vol.29, no.1, pp.59-66, 2010 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2010
  • Doi Number: 10.4149/gpb_2010_01_59
  • Journal Name: GENERAL PHYSIOLOGY AND BIOPHYSICS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.59-66
  • Keywords: Radiofrequency radiation, Pregnant exposure, MDA, 8-OHdG, Brain, ELECTROMAGNETIC-RADIATION, OXIDATIVE STRESS, STRAND BREAKS, MOBILE PHONE, EXPOSURE, IRRADIATION, TELEPHONES, FETUSES, CELLS, FETAL

Abstract

The concerns of people on possible adverse health effects of radiofrequency radiation (RFR) generated from mobile phones as well as their supporting transmitters (base stations) have increased markedly. RFR effect on oversensitive people, such as pregnant women and their developing fetuses, and older people is another source of concern that should be considered. In this study, oxidative DNA damage and lipid peroxidation levels in the brain tissue of pregnant and non-pregnant New Zealand White rabbits and their newborns exposed to RFR were investigated. Thirteen-month-old rabbits were studied in four groups as non-pregnant-control, non-pregnant-RFR exposed, pregnant-control and pregnant-RFR exposed. They were exposed to RFR (1800 MHz GSM; 14 Vim as reference level) for 15 min/day during 7 days. Malondialdehyde (MDA) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels were analyzed. MDA and 8-OHdG levels of non-pregnant and pregnant-RFR exposed animals significantly increased with respect to controls (p < 0.001, Mann-Whitney test). No difference was found in the newborns (p > 0.05, Mann-Whitney). There exist very few experimental studies on the effects of RFR during pregnancy. It would be beneficial to increase the number of these studies in order to establish international standards for the protection of pregnant women from RFR.