Copy For Citation
Ayyildiz M., Coskun Ş., Yildirim M., Agar E.
EPILEPSIA, vol.48, no.7, pp.1388-1395, 2007 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
48
Issue:
7
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Publication Date:
2007
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Doi Number:
10.1111/j.1528-1167.2007.01080.x
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Journal Name:
EPILEPSIA
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.1388-1395
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Keywords:
epileptiform activity, glutathione, lipid peroxidation, penicillin, vitamin C, LIPID-PEROXIDATION, GLUTATHIONE-PEROXIDASE, OXIDATIVE STRESS, TRACE-ELEMENTS, FREE-RADICALS, IN-VITRO, ETHANOL, ELECTROLYTES, HIPPOCAMPUS, SYSTEMS
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Gazi University Affiliated:
Yes
Abstract
Purpose: Epileptic seizure results from excessive discharge in a population of hyperexcitable neurons. A number of studies help to document the effects of active oxygen free radical scavengers such as alpha-tocopherol or ascorbic acid (vitamin C). In the present study, we examined the effects of ascorbic acid, at the six different doses, on penicillin-induced epileptiform activity.