Novel antifouling oligo(ethylene glycol) methacrylate particles via surfactant-free emulsion polymerization


Buyukserin F., Camli S. T. , Yavuz M. S. , Budak G. G.

JOURNAL OF COLLOID AND INTERFACE SCIENCE, vol.355, no.1, pp.76-80, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 355 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jcis.2010.11.081
  • Title of Journal : JOURNAL OF COLLOID AND INTERFACE SCIENCE
  • Page Numbers: pp.76-80

Abstract

The use of particle formulations with antifouling surface properties attracts increasing interest in several biotechnological applications. Majority of these studies utilize a poly(ethylene glycol) coating to render the corresponding surface nonrecognizable to biological macromolecules. Herein, we report a simple way to prepare novel antifouling colloids composed of oligo(ethylene glycol) backbones via surfactant-free emulsion polymerization. Monodisperse cross-linked poly(ethylene glycol) ethyl ether methacrylate particles were characterized by dynamic light scattering and transmission electron microscopy. The effects of monomer, cross-linker and initiator on particle characteristics were investigated. More importantly, a prominent blockage of bovine serum albumin adsorption was obtained for the poly(ethylene glycol)-based sub-micron (similar to 200 nm) particles when compared with similar-sized poly(methyl methacrylate) counterparts. (C) 2010 Elsevier Inc. All rights reserved.