Treatment-related alterations of imaging findings in osteoid osteoma after percutaneous radiofrequency ablation.

Erbaş G., Sendur H. N., Kılıç H. K., Cindil E., Öner A. Y., Tokgöz N., ...More

Skeletal radiology, vol.48, no.11, pp.1697-1703, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 11
  • Publication Date: 2019
  • Doi Number: 10.1007/s00256-019-03185-1
  • Journal Name: Skeletal radiology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1697-1703
  • Keywords: Osteoid osteoma, Radiofrequency ablation, Magnetic resonance imaging, Computed tomography, Follow-up, THERMAL ABLATION, MRI
  • Gazi University Affiliated: Yes


Objectives We aimed to report the long-term outcomes of osteoid osteoma patients and to determine CT and dynamic contrast-enhanced MR imaging characteristics of radiofrequency ablation (RFA) treatment related changes of osteoid osteoma between follow-up periods. Materials and methods Thirty patients (seven female, 23 male) who underwent CT-guided RFA of osteoid osteoma were included. Follow-up imaging examinations were divided into two subgroups; first (1-3 months) and second (> 6 months) periods. Nidus size, calcification, cortical thickening, maximum signal intensity (SImax), time of SImax (Tmax), slope of signal intensity-time (SIT) curves were noted. CT and dynamic MR imaging findings were compared between follow-up periods. Results Clinical success rate was 100%. The mean of OO nidi size was 5.85 +/- 1.98 mm before treatment. There was a significant difference for OO nidi sizes between pretreatment and second follow-up period examinations (p = 0.002). SImax and slope of SIT curves of all patients (100%) showed decrease on follow-up MRIs. There was a significant decrease for SImax values between pretreatment and second follow-up period. There was a significant decrease for slope of SIT curves between pretreatment and both follow-up periods. Conclusions RFA is an effective and safe treatment choice for osteoid osteomas. On follow-up imaging, slope of SIT curve and Tmax have the most important positive predictive value for long-term outcomes and single dynamic contrast-enhanced MRI within first 3 months after treatment may be sufficient for symptom-free patients.