EFFECTS OF TAURINE AND AGE ON PLASMA OXIDATIVE STRESS PARAMETERS AND ANTIOXIDANTS IN RATS


Kilic N., Yildirim Z.

OXIDATION COMMUNICATIONS, vol.34, no.2, pp.446-456, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 2
  • Publication Date: 2011
  • Journal Name: OXIDATION COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.446-456
  • Gazi University Affiliated: Yes

Abstract

The aim of the present study was to investigate the effects of taurine on advanced oxidation protein products (AOPPs), malondialdehyde (MDA), nitric oxide (NO), glutathione (GSH), superoxide dismutase (SOD), glutathione peroxidase (GPx), zinc (Zn) and copper (Cu) in young and middle-aged rat plasma. Middle-aged (13-14 months of age) male albino Wistar rats were divided into two groups as the middle-aged control and the middle-aged taurine groups. Young (6-7 weeks of age) male albino Wistar rats were divided into two groups as the young control and the young taurine groups. While the rats in the control groups were given 0.5 ml of isotonic sodium chloride, the others were given taurine intraperitonally at a single dose of 200 mg/kg/day for 7 days.