Effects of Vascular Endothelial Growth Factor on Ischemic Spinal Cord Injury Caused by Aortic Cross-Clamping in Rabbits

Oyar, Eser; Kardes, Oezguer; Korkmaz, Ayhan; ÖMEROĞLU, SUNA

doi:10.1016/j.jss.2008.01.006

Effects of Vascular Endothelial Growth Factor on Ischemic Spinal Cord Injury Caused by Aortic Cross-Clamping in Rabbits

Oyar E. O., Kardes O., Korkmaz A., ÖMEROĞLU S.

JOURNAL OF SURGICAL RESEARCH, cilt.151, sa.1, ss.94-99, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 151 Sayı: 1
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.jss.2008.01.006
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.94-99
Anahtar Kelimeler: VEGF, ischemia-reperfusion, oxidative stress, spinal cord, BRAIN, VEGF, ANGIOGENESIS, GLUTATHIONE, EXPRESSION, HYPOXIA, DAMAGE, GENES, RAT
Gazi Üniversitesi Adresli: Evet

Özet

Background. Spinal cord injury remains a devastating complication of thoracic and thoracoabdominal aortic operations. We aim to investigate neuro-protective role of vascular endothelial growth factor (VEGF) administered to rabbits after occlusion against ischemiareperfusion (I/R) injury.